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AdipoGen Life Sciences
Darcin (mouse) (rec.) (untagged)
230
CHF
CHF 230.00
In stock
AG-40B-0078-C01010 µgCHF 230.00
AG-40B-0078-30103 x 10 µgCHF 455.00
| Product Details | |
|---|---|
| Synonyms | Mup20; Mouse Urinary Protein 20; Major Urinary Protein 24 |
| Product Type | Protein |
| Properties | |
| Source/Host | E. coli |
| Sequence | Darcin (mouse) (aa 20-181) is untagged. |
| Crossreactivity | Mouse |
| MW | ~17kDa (SDS-PAGE) |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.1EU/μg purified protein (LAL test; Lonza). |
| Concentration | 0.1mg/ml after reconstitution. |
| Reconstitution | Reconstitute with 100μl sterile distilled water. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data | UniProt link Q5FW60: Darcin (mouse) |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Use/Stability |
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Darcin (also called Mup20) belongs to the family of major urinary proteins (MUPs), a subfamily of proteins found in abundance in the urine. Like all MUPs, Darcin is a member of the lipocalin family of ligand-binding proteins, and preferentially binds the volatile pheromome (S)-2-sec-butyl-4,5-dihydrothiazole (SBT). Darcin is present in the urine of male and acts as a sex pheromone that elicits female sexual attraction to a male's urine scent. Recently it was reported that Darcin elicits a complex and variable behavioural repertoire that consists of attraction, ultrasonic vocalization and urinary scent marking, and also serves as a reinforcer in learning paradigms. Darcin reinforces behaviours that promote mate encounters and mate selection. Recombinant Darcin shows similar activity compared to natural Darcin.